Tenofovir-induced kidney disease: an acquired renal tubular mitochondriopathy
نویسندگان
چکیده
منابع مشابه
Renal tubular dysfunction associated with tenofovir therapy.
OBJECTIVE To describe the i ncidence a nd cha racteristics of Tenofovir (TDF) induced nephrotoxicity among people living with HIV AIDS (PLHA) receiving TDF based anti-retroviral therapy (ART) at Christian Medical College, Vellore. METHOD Medical record review of all the PLHA who is being enrolled and followed up at the ART clinic at CMC, Vellore. RESULTS From 2006-11, a total of 274 PLHA ha...
متن کاملMechanism of active renal tubular efflux of tenofovir.
Tenofovir (TFV) undergoes renal elimination by a combination of glomerular filtration and active tubular secretion. While transporter-mediated uptake of TFV from the blood into proximal-tubule cells has been well characterized, comparatively little is known about the efflux system responsible for transporting TFV into the lumen during active tubular secretion. Therefore, members of the ATP-bind...
متن کاملRenal Tubular Disease
Type 1 (classic distal) renal tubular acidosis [2] Inability to form an acid urine in the distal tubule [3] . May be inherited as a primary disorder or associated with autoimmune disorders (eg, Sjögren's syndrome, systemic lupus erythematosus (SLE)) [4] , hyperparathyroidism, analgesic nephropathy, renal transplant rejection, obstructive uropathy and chronic urinary tract infections (UTIs). Wit...
متن کاملRenal Tubular Disease
Type 1 (classic distal) renal tubular acidosis [2] Inability to form an acid urine in the distal tubule [3] . May be inherited as a primary disorder or associated with autoimmune disorders (eg, Sjögren's syndrome, systemic lupus erythematosus (SLE)) [4] , hyperparathyroidism, analgesic nephropathy, renal transplant rejection, obstructive uropathy and chronic urinary tract infections (UTIs). Wit...
متن کاملRenal Tubular Disease
Type 1 (classic distal) renal tubular acidosis [2] Inability to form an acid urine in the distal tubule [3] . May be inherited as a primary disorder or associated with autoimmune disorders (eg, Sjögren's syndrome, systemic lupus erythematosus (SLE)) [4] , hyperparathyroidism, analgesic nephropathy, renal transplant rejection, obstructive uropathy and chronic urinary tract infections (UTIs). Wit...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2010
ISSN: 0085-2538
DOI: 10.1038/ki.2010.344